Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 2/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13620403 | 0.84 | BAZ2B (0.41) | KDM4EMAPK1TP53MAPTMEN1 | |
| SCHEMBL13662212 | 0.83 | VKORC1 (0.42) | CHRM1KDM4EMAPK1HTTSMN1; SMN2 | |
| SCHEMBL1127325 | 0.80 | IDO1 (0.35) | FEN1CHRM1 | |
| SCHEMBL1127254 | 0.78 | ALDH1A1 (0.48) | KDM4EMAPK1HTTSMN1; SMN2MAPT | |
| SCHEMBL1128375 | 0.76 | PTGES (0.48) | KDM4EMAPK1HTTVKORC1TP53 | |
| SCHEMBL1127987 | 0.75 | ALDH1A1 (0.49) | KDM4EMAPK1HTTSMN1; SMN2TP53 | |
| SCHEMBL1127411 | 0.73 | ALDH1A1 (0.43) | KDM4EMAPK1HTTSMN1; SMN2MAPT | |
| SCHEMBL13662302 | 0.73 | IDH1 (0.47) | VKORC1TP53MAPTKMT2APOLB | |
| SCHEMBL1127428 | 0.72 | ALDH1A1 (0.45) | KDM4EMAPK1HTTSMN1; SMN2MAPT | |
| SCHEMBL1128142 | 0.72 | KDM4E (0.46) | KDM4EMAPK1SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134616-A2 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2009-11-05 | — | — | WO | disclosed |