Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12410885 | 0.79 | KMT2A (0.38) | KMT2ACYP1A2CYP2D6ALDH1A1TP53 | |
| SCHEMBL4982011 | 0.73 | KMT2A (0.44) | KMT2ACYP1A2CYP2D6ALDH1A1TP53 | |
| SCHEMBL2180470 | 0.72 | KMT2A (0.46) | KMT2ACYP1A2CYP2D6ALDH1A1TP53 | |
| SCHEMBL14440482 | 0.72 | MEN1 (0.31) | KMT2AMEN1 | |
| Bromide SCHEMBL25199975 | 0.71 | CYP1A2 (0.44) | KMT2ACYP1A2CYP2D6ALDH1A1MAPT | |
| SCHEMBL5573253 | 0.71 | KMT2A (0.47) | KMT2ACYP1A2CYP2D6ALDH1A1TP53 | |
| SCHEMBL30996203 | 0.71 | CYP1A2 (0.55) | KMT2ACYP1A2CYP2D6TP53LMNA | |
| SCHEMBL12024139 | 0.70 | ALDH1A1 (0.54) | KMT2AALDH1A1TP53LMNAMAPT | |
| SCHEMBL9222528 | 0.70 | OPRM1 (0.38) | KMT2ACYP1A2CYP2D6ALDH1A1TP53 | |
| SCHEMBL9738900 | 0.70 | KMT2A (0.46) | KMT2ACYP1A2CYP2D6ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090280060-A1 | PHOTOCHROMIC PROBES | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2009-11-12 | — | — | US | disclosed |
| US-20090280060-A1 | PHOTOCHROMIC PROBES | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2009-11-12 | — | — | US | disclosed |
| US-20070195309-A1 | PHOTOCHROMIC PROBES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-08-23 | — | — | US | disclosed |
| US-20070195309-A1 | PHOTOCHROMIC PROBES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070195309-A1 | PHOTOCHROMIC PROBES | ORAI1, TRPC1, STIM1 | KMT2A 4480/4885CYP1A2 3441/4885CYP2D6 2032/4885 |
| US-20090280060-A1 | PHOTOCHROMIC PROBES | ORAI1, TRPC1, STIM1 | KMT2A 4480/4885CYP1A2 3441/4885CYP2D6 2032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.