Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 7/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19116479 | 0.85 | KMT2A (0.42) | KMT2ACYP1A2CYP2D6MAPTALDH1A1 | |
| SCHEMBL26207778 | 0.84 | MAPT (0.38) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL13247890 | 0.84 | KMT2A (0.41) | KMT2ACYP1A2CYP2D6MAPTALDH1A1 | |
| SCHEMBL14440502 | 0.84 | KMT2A (0.41) | KMT2ACYP1A2CYP2D6MAPTALDH1A1 | |
| SCHEMBL14428040 | 0.82 | KMT2A (0.40) | KMT2ACYP1A2CYP2D6MAPTALDH1A1 | |
| SCHEMBL5573253 | 0.82 | KMT2A (0.47) | KMT2ACYP1A2CYP2D6MAPTALDH1A1 | |
| SCHEMBL30996203 | 0.82 | CYP1A2 (0.55) | KMT2ACYP1A2CYP2D6MAPTLMNA | |
| SCHEMBL8942258 | 0.81 | OPRM1 (0.47) | KMT2ACYP1A2CYP2D6MAPTALDH1A1 | |
| SCHEMBL2180470 | 0.81 | KMT2A (0.46) | KMT2ACYP1A2CYP2D6MAPTALDH1A1 | |
| SCHEMBL9738900 | 0.81 | KMT2A (0.46) | KMT2ACYP1A2CYP2D6MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100501462-C | Filter and cyanine compound | NIPPON KAYAKU KK (JP) | 2009-06-17 | — | — | CN | disclosed |
| US-20080048155-A1 | Filter and Cyanine Compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2008-02-28 | — | — | US | disclosed |
| EP-1806605-A1 | FILTER AND CYANINE COMPOUND | Nippon Kayaku Kabushiki Kaisha (JP) | 2007-07-11 | — | — | EP | disclosed |
| CN-1969205-A | Filter and cyanine compound | NIPPON KAYAKU KK (JP) | 2007-05-23 | — | — | CN | disclosed |
| US-20060105257-A1 | Indolenine compound, near infrared absorber, and toner containing the same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2006-05-18 | — | — | US | disclosed |
| EP-1541556-A1 | INDOLENINE COMPOUND, NEAR INFRARED ABSORBER, AND TONER CONTAINING THE SAME | Nippon Kayaku Kabushiki Kaisha (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-5017698-A | Spirooxazine photochromic compounds | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0350009-A1 | Photochromic compound and photochromic composition | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080048155-A1 | Filter and Cyanine Compound | IK, CRYZ, C9 | KMT2A 2621/4885CYP1A2 3981/4885CYP2D6 4562/4885 |
| US-20060105257-A1 | Indolenine compound, near infrared absorber, and toner containing the same | IDO1, CRY2, CRY1 | KMT2A 2153/4885CYP1A2 1055/4885CYP2D6 3197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.