Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.45 |
| ▸ | BAD | Q92934 | 3/20 | 0.45 |
| ▸ | CNR2 | P34972 | 5/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2033486 | 0.85 | MCL1 (0.52) | MCL1BADCNR2CNR1ALDH1A1 | |
| SCHEMBL2037230 | 0.84 | CNR2 (0.60) | MCL1BADCNR2CNR1SMN1; SMN2 | |
| SCHEMBL12484505 | 0.83 | LTB4R (0.49) | MCL1BADCNR2CNR1ALDH1A1 | |
| SCHEMBL17908066 | 0.78 | ABCG2 (0.50) | MCL1BADALDH1A1MAPTHTT | |
| SCHEMBL2035666 | 0.78 | P2RX7 (0.48) | MCL1BADCNR2CNR1ALDH1A1 | |
| SCHEMBL1127285 | 0.76 | PLK1 (0.57) | CNR2CNR1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL2034373 | 0.74 | ALDH1A1 (0.50) | MCL1BADCNR2CNR1ALDH1A1 | |
| SCHEMBL7835036 | 0.73 | CA12 (0.41) | MCL1BADALDH1A1LTB4RLTB4R2 | |
| SCHEMBL13619973 | 0.72 | HPGD (0.50) | CNR2CNR1ALDH1A1MAPTKDM4E | |
| SCHEMBL2044464 | 0.72 | P2RX7 (0.50) | MCL1BADCNR2CNR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134616-A2 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2009-11-05 | — | — | WO | disclosed |