Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.40 |
| ▸ | TCF7L2 | Q9NQB0 | 3/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.38 |
| ▸ | CD38 | P28907 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12948785 | 0.92 | DRD2 (0.45) | HDAC1KMT2AESR1MAPTMAPK10 | |
| SCHEMBL13619317 | 0.87 | ERAP1 (0.39) | KMT2AMEN1NR1H4ERAP1SMN1; SMN2 | |
| SCHEMBL12585213 | 0.81 | ELANE (0.48) | HDAC1KMT2AESR1MAPTMAPK10 | |
| SCHEMBL12585207 | 0.81 | PTGER4 (0.54) | PTGER4 | |
| SCHEMBL12583794 | 0.80 | ELANE (0.49) | HDAC1KMT2AESR1MAPTMAPK10 | |
| SCHEMBL12948674 | 0.78 | DRD2 (0.41) | KMT2AMAPTMEN1ERAP1ALDH1A1 | |
| SCHEMBL13619313 | 0.76 | KCNH2 (0.39) | HDAC1KMT2AMAPTMEN1NR1H4 | |
| SCHEMBL12583793 | 0.75 | DRD2 (0.47) | HDAC1KMT2AESR1MAPTMAPK10 | |
| SCHEMBL12583800 | 0.72 | DRD2 (0.47) | HDAC1KMT2AESR1MAPTMAPK10 | |
| SCHEMBL12583797 | 0.72 | DRD2 (0.47) | HDAC1KMT2AESR1MAPTMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009139373-A1 | AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2009-11-19 | — | — | WO | disclosed |