Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | GALK1 | P51570 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12948674 | 0.91 | DRD2 (0.41) | ERAP1ABCC1ABCG2MEN1KMT2A | |
| SCHEMBL13619313 | 0.89 | KCNH2 (0.39) | ERAP1POLBNR1H4MEN1KMT2A | |
| SCHEMBL13620082 | 0.87 | HDAC1 (0.43) | ERAP1NR1H4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12948806 | 0.82 | GAA (0.51) | POLBATMABCC1ABCG2RORC | |
| SCHEMBL13619261 | 0.80 | DHODH (0.39) | POLBMEN1KMT2AKDM4E | |
| SCHEMBL10085248 | 0.80 | PTGER4 (0.49) | — | |
| SCHEMBL12585199 | 0.80 | LMNA (0.41) | POLBATMABCC1ABCG2RORC | |
| SCHEMBL12583769 | 0.79 | RAB9A (0.49) | POLBABCG2MEN1KMT2ANPC1 | |
| SCHEMBL12948785 | 0.78 | DRD2 (0.45) | MEN1KMT2AGALK1KDM4E | |
| SCHEMBL988503 | 0.74 | EGFR (0.46) | ABCC1ABCG2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009139373-A1 | AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2009-11-19 | — | — | WO | disclosed |