SCHEMBL13620140

SCHEMBL13620140

Cc1c(-c2ccc(-c3ccc(N(c4ccccc4)c4ccc(-c5ccccc5)cc4)cc3)cc2)ccc(-n2c3ccccc3c3ccccc32)c1C

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.33
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 2/20 0.33
ATM Q13315 1/20 0.33
TSPO P30536 1/20 0.33
GSK3B P49841 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
MAPT P10636 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13620163 0.91 TSPO (0.32) TSPOHSD17B10
SCHEMBL13620164 0.90 MAPT (0.32) TSPOMAPT
SCHEMBL13620144 0.88 L3MBTL1 (0.45) L3MBTL1ALDH1A1KDM4EATMTSPO
SCHEMBL13620149 0.86 TSPO (0.32) TSPOHSD17B10
SCHEMBL20413205 0.85 NPY5R (0.32) ATMTSPO
SCHEMBL25725170 0.85 L3MBTL1 (0.38) L3MBTL1ALDH1A1KDM4EATMTSPO
SCHEMBL24307532 0.83 L3MBTL1 (0.41) L3MBTL1ALDH1A1KDM4EATMTSPO
SCHEMBL24307527 0.83 L3MBTL1 (0.41) L3MBTL1ALDH1A1KDM4EATMTSPO
SCHEMBL24374213 0.83 L3MBTL1 (0.39) L3MBTL1ALDH1A1KDM4EATMHSD17B10
SCHEMBL19269083 0.83 PTGDR2 (0.35) L3MBTL1ALDH1A1TSPOMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8852758-B2 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic device using the aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-10-07 US disclosed
US-8852758-B2 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic device using the aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-10-07 US disclosed
US-20130076237-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Aromatic Amine Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-28 US disclosed
US-20130076237-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Aromatic Amine Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-28 US disclosed
US-8318322-B2 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic device using aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-11-27 US disclosed
US-8318322-B2 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic device using aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-11-27 US disclosed
US-20090284143-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Aromatic Amine Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-11-19 US disclosed
US-20090284143-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Aromatic Amine Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130076237-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Aromatic Amine Compound TYR, PAH, NAT1 L3MBTL1 1077/4885ALDH1A1 58/4885KDM4E 1140/4885
US-20090284143-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Aromatic Amine Compound TYR, PAH, NAT1 L3MBTL1 1073/4885ALDH1A1 47/4885KDM4E 1176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.