SCHEMBL13620149

SCHEMBL13620149

Cc1cc(-n2c3ccccc3c3ccccc32)c(C)cc1-c1ccc(-c2ccc(N(c3ccccc3)c3ccc(-c4ccccc4)cc3)cc2)c(C)c1C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSPO P30536 1/20 0.32
ESR2 Q92731 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13620161 0.93 TSPO (0.34) TSPOESR2HSD17B10
SCHEMBL13620139 0.92 TSPO (0.34) TSPOESR2HSD17B10
SCHEMBL13620163 0.91 TSPO (0.32) TSPOESR2HSD17B10
SCHEMBL13620140 0.86 L3MBTL1 (0.33) TSPOHSD17B10
SCHEMBL13620155 0.85 TSPO (0.32) TSPO
SCHEMBL13620154 0.84 TSPO (0.32) TSPO
SCHEMBL13620147 0.84 KDM4E (0.35) TSPO
SCHEMBL13620158 0.82 KDM4E (0.36) TSPOESR2
SCHEMBL13620144 0.82 L3MBTL1 (0.45) TSPOHSD17B10
SCHEMBL13620164 0.81 MAPT (0.32) TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8852758-B2 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic device using the aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-10-07 US disclosed
US-8852758-B2 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic device using the aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-10-07 US disclosed
US-20130076237-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Aromatic Amine Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-28 US disclosed
US-20130076237-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Aromatic Amine Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-28 US disclosed
US-8318322-B2 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic device using aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-11-27 US disclosed
US-8318322-B2 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic device using aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-11-27 US disclosed
US-20090284143-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Aromatic Amine Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-11-19 US disclosed
US-20090284143-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Aromatic Amine Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130076237-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Aromatic Amine Compound TYR, PAH, NAT1 TSPO 3559/4885ESR2 381/4885HSD17B10 2858/4885
US-20090284143-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Aromatic Amine Compound TYR, PAH, NAT1 TSPO 3506/4885ESR2 386/4885HSD17B10 2644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.