SCHEMBL13620181

SCHEMBL13620181

CCCCc1ccc2c(c1)c1cc(CCCC)ccc1n2-c1ccc(-c2ccc(-c3ccc(N(c4ccccc4)c4ccc(-c5ccccc5)cc4)cc3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.42
EP300 Q09472 1/20 0.41
KAT2A Q92830 1/20 0.41
KAT2B Q92831 1/20 0.41
RORA P35398 2/20 0.40
RORC P51449 2/20 0.40
RORB Q92753 2/20 0.40
PLA2G4A P47712 1/20 0.38
PSMB5 P28074 1/20 0.38
PGR P06401 2/20 0.36
RARB P10826 1/20 0.36
MAPK8 P45983 1/20 0.36
UCHL3 P15374 1/20 0.36
TSPO P30536 1/20 0.36
DHODH Q02127 1/20 0.35
LTB4R2 Q9NPC1 1/20 0.35
PTGES O14684 1/20 0.35
CTSV O60911 1/20 0.34
CTSL P07711 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24004264 0.96 RORA (0.41) HSD11B1EP300KAT2AKAT2BRORA
SCHEMBL13932498 0.95 RORA (0.41) HSD11B1EP300KAT2AKAT2BRORA
SCHEMBL23800897 0.94 RORA (0.47) HSD11B1RORARORCRORBPLA2G4A
SCHEMBL14039244 0.93 PLA2G4A (0.40) HSD11B1EP300KAT2AKAT2BRORA
SCHEMBL262630 0.92 EP300 (0.39) HSD11B1EP300KAT2AKAT2BRORA
SCHEMBL23812620 0.92 RORA (0.37) HSD11B1EP300KAT2AKAT2BRORA
SCHEMBL13932489 0.91 RORA (0.44) RORARORCRORBPLA2G4APGR
SCHEMBL10175855 0.91 MAPK8 (0.39) HSD11B1EP300KAT2AKAT2BRORA
SCHEMBL14029408 0.90 RORA (0.38) HSD11B1EP300KAT2AKAT2BRORA
SCHEMBL24004262 0.89 BCHE (0.38) HSD11B1EP300KAT2AKAT2BRORA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8852758-B2 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic device using the aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-10-07 US disclosed
US-8852758-B2 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic device using the aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-10-07 US disclosed
US-20130076237-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Aromatic Amine Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-28 US disclosed
US-20130076237-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Aromatic Amine Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-28 US disclosed
US-8318322-B2 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic device using aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-11-27 US disclosed
US-8318322-B2 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic device using aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-11-27 US disclosed
US-20090284143-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Aromatic Amine Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-11-19 US disclosed
US-20090284143-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Aromatic Amine Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130076237-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Aromatic Amine Compound TYR, PAH, NAT1 HSD11B1 2735/4885EP300 947/4885KAT2A 1573/4885
US-20090284143-A1 Aromatic Amine Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Aromatic Amine Compound TYR, PAH, NAT1 HSD11B1 2471/4885EP300 1036/4885KAT2A 1594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.