SCHEMBL10175855

SCHEMBL10175855

CCCCc1ccc2c(c1)c1cc(CCCC)ccc1n2-c1ccc(N(c2ccccc2)c2ccc(-c3ccc4c(-c5ccccc5)c5ccccc5c(-c5ccccc5)c4c3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 1/20 0.39
EP300 Q09472 1/20 0.38
KAT2A Q92830 1/20 0.38
KAT2B Q92831 1/20 0.38
RORA P35398 2/20 0.37
RORC P51449 2/20 0.37
RORB Q92753 2/20 0.37
TSPO P30536 2/20 0.37
HSD11B1 P28845 2/20 0.36
ICMT O60725 1/20 0.34
PGR P06401 2/20 0.33
PLA2G4A P47712 1/20 0.33
LTB4R2 Q9NPC1 1/20 0.32
DHODH Q02127 1/20 0.32
PSMB5 P28074 1/20 0.32
PTPN1 P18031 1/20 0.32
CTSV O60911 1/20 0.32
CTSL P07711 1/20 0.32
CNR1 P21554 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL262630 0.98 EP300 (0.39) MAPK8EP300KAT2AKAT2BRORA
SCHEMBL10161081 0.96 MAPK8 (0.38) MAPK8EP300KAT2AKAT2BRORA
SCHEMBL14029408 0.96 RORA (0.38) MAPK8EP300KAT2AKAT2BRORA
SCHEMBL10161132 0.95 MAPK8 (0.36) MAPK8EP300KAT2AKAT2BRORA
SCHEMBL10175858 0.94 TSPO (0.36) MAPK8EP300KAT2AKAT2BRORA
SCHEMBL262076 0.92 TSPO (0.37) EP300KAT2AKAT2BRORARORC
SCHEMBL262206 0.92 EP300 (0.43) MAPK8EP300KAT2AKAT2BRORA
SCHEMBL14521315 0.91 RORA (0.39) MAPK8EP300KAT2AKAT2BRORA
SCHEMBL13620181 0.91 HSD11B1 (0.42) MAPK8EP300KAT2AKAT2BRORA
SCHEMBL10160294 0.90 PLA2G4A (0.35) MAPK8RORARORCRORBTSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8288012-B2 Anthracene derivatives and light-emitting devices using the anthracene derivatives SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-10-16 US disclosed
US-8288012-B2 Anthracene derivatives and light-emitting devices using the anthracene derivatives SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-10-16 US disclosed
US-20120211728-A1 Light-Emitting Element, Light-Emitting Device, and Electronic Appliance SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-08-23 US disclosed
US-8101289-B2 Light-emitting element, light-emitting device, and electronic appliance SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-01-24 US disclosed
US-8101289-B2 Light-emitting element, light-emitting device, and electronic appliance SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-01-24 US disclosed
US-20090058278-A1 Light-Emitting Element, Light-Emitting Device, and Electronic Appliance SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-03-05 US disclosed
US-20090058278-A1 Light-Emitting Element, Light-Emitting Device, and Electronic Appliance SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-03-05 US disclosed
EP-2031036-A1 Light-emitting element, light-emitting device, and electronic appliance SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-03-04 EP disclosed
US-20090004506-A1 Anthracene Derivatives and Light-Emitting Devices Using the Anthracene Derivatives SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-01-01 US disclosed
US-20090004506-A1 Anthracene Derivatives and Light-Emitting Devices Using the Anthracene Derivatives SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090004506-A1 Anthracene Derivatives and Light-Emitting Devices Using the Anthracene Derivatives CRY1, CYP1A1, GLB1 MAPK8 3313/4885EP300 4183/4885KAT2A 3034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.