Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.41 |
| ▸ | FDPS | P14324 | 9/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27324212 | 0.86 | LMNA (0.44) | SMPD1FDPSGGPS1 | |
| SCHEMBL13620249 | 0.84 | SMPD1 (0.42) | SMPD1FDPSGGPS1 | |
| SCHEMBL28255184 | 0.84 | SMPD1 (0.42) | SMPD1FDPSGGPS1 | |
| SCHEMBL27891743 | 0.84 | SMPD1 (0.42) | SMPD1FDPSGGPS1 | |
| SCHEMBL4392179 | 0.84 | HTT (0.52) | SMPD1FDPSGGPS1CES1 | |
| SCHEMBL28001874 | 0.83 | FDPS (0.38) | SMPD1FDPSGGPS1 | |
| SCHEMBL10397171 | 0.82 | TSHR (0.36) | SMPD1FDPSGGPS1CES1 | |
| SCHEMBL27750983 | 0.81 | CES1 (0.40) | SMPD1FDPSGGPS1CES1 | |
| SCHEMBL8861613 | 0.81 | SMPD1 (0.40) | SMPD1FDPSGGPS1 | |
| SCHEMBL27751867 | 0.79 | MEN1 (0.36) | SMPD1FDPSGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9925267-B2 | Polylactide compositions and uses thereof | UNIVERSITY OF GENEVA (CH) | 2018-03-27 | — | — | US | disclosed |
| US-20160367680-A1 | POLYLACTIDE COMPOSITIONS AND USES THEREOF | UNIVERSITY OF GENEVA (CH) | 2016-12-22 | — | — | US | disclosed |
| US-20090281068-A1 | POLYLACTIDE COMPOSITIONS AND USES THEREOF | UNIVERSITY OF GENEVA | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281068-A1 | POLYLACTIDE COMPOSITIONS AND USES THEREOF | LPXN, PUF60, DDOST | SMPD1 526/4885FDPS 373/4885GGPS1 459/4885 |
| US-20160367680-A1 | POLYLACTIDE COMPOSITIONS AND USES THEREOF | LPXN, PUF60, DDOST | SMPD1 526/4885FDPS 373/4885GGPS1 459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.