Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.42 |
| ▸ | FDPS | P14324 | 9/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13620249 | 1.00 | SMPD1 (0.42) | SMPD1FDPSGGPS1MEN1MAPT | |
| SCHEMBL28255184 | 1.00 | SMPD1 (0.42) | SMPD1FDPSGGPS1MEN1MAPT | |
| SCHEMBL8641529 | 0.91 | SMPD1 (0.32) | SMPD1FDPSGGPS1 | |
| SCHEMBL11548756 | 0.89 | FAAH (0.46) | MEN1MAPTKMT2AATM | |
| SCHEMBL13620256 | 0.84 | SMPD1 (0.41) | SMPD1FDPSGGPS1 | |
| SCHEMBL8861613 | 0.83 | SMPD1 (0.40) | SMPD1FDPSGGPS1CES2 | |
| SCHEMBL6064783 | 0.81 | TSHR (0.40) | SMPD1FDPSGGPS1MEN1MAPT | |
| SCHEMBL1563330 | 0.81 | TSHR (0.40) | SMPD1FDPSGGPS1MEN1MAPT | |
| Acetic Acid SCHEMBL27586910 | 0.81 | ALDH1A1 (0.34) | SMPD1FDPSGGPS1MEN1MAPT | |
| SCHEMBL9426138 | 0.81 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108619161-A | Acyclic nucleoside phosphonate diester | 加利福尼亚大学董事会 | 2018-10-09 | — | — | CN | disclosed |
| CN-105246902-B | acyclic nucleoside phosphonate diesters | 加利福尼亚大学董事会 | 2018-05-04 | — | — | CN | disclosed |
| CN-107056838-A | Acyclic nucleoside phosphonate diester | 加利福尼亚大学董事会 | 2017-08-18 | — | — | CN | disclosed |
| CN-105246902-A | Acyclic nucleoside phosphonate diesters | UNIV CALIFORNIA | 2016-01-13 | — | — | CN | disclosed |
| CN-102939291-A | Phosphonates with reduced toxicity for treatment of viral infections | UNIV CALIFORNIA | 2013-02-20 | — | — | CN | disclosed |