Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | HTT | P42858 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 7/20 | 0.34 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | MITF | O75030 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14385184 | 0.80 | HTT (0.50) | ALDH1A1HTTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL13620347 | 0.78 | KAT2B (0.36) | KAT2BBRD9GABRA1GABRB2ALDH1A1 | |
| SCHEMBL14074017 | 0.78 | KAT2B (0.58) | KAT2BBRD9ALDH1A1RAB9AMAPT | |
| SCHEMBL17738012 | 0.74 | SMN1; SMN2 (0.50) | KAT2BBRD9ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL13562543 | 0.71 | NPBWR1 (0.56) | ALDH1A1HTTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL16884990 | 0.69 | — | — | |
| SCHEMBL18454995 | 0.67 | HTT (0.59) | ALDH1A1HTTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL18532426 | 0.67 | GAA (0.56) | ALDH1A1HTTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL18446084 | 0.65 | RAB9A (0.78) | KAT2BBRD9ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL18979930 | 0.64 | NPSR1 (0.76) | ALDH1A1HTTSMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123264-A1 | Heterocyclic derivatives as abnormal cannabidiols agents for lowering intraocular pressure | Allergan, Inc. (US) | 2009-11-25 | — | — | EP | disclosed |