Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 7/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13620651 | 0.84 | MAPT (0.57) | FDPSMAPTSMN1; SMN2NPSR1LMNA | |
| SCHEMBL6229249 | 0.83 | FDPS (0.63) | FDPSMAPTSMN1; SMN2NPSR1LMNA | |
| SCHEMBL18874317 | 0.79 | FDPS (0.51) | FDPSMAPTSMN1; SMN2NPSR1LMNA | |
| SCHEMBL9078005 | 0.78 | FDPS (0.72) | FDPSMAPTSMN1; SMN2NPSR1LMNA | |
| SCHEMBL31331562 | 0.78 | FDPS (0.72) | FDPSMAPTSMN1; SMN2NPSR1LMNA | |
| SCHEMBL13620606 | 0.77 | MTNR1A (0.49) | FDPSMAPTSMN1; SMN2NPSR1LMNA | |
| SCHEMBL7661907 | 0.77 | FDPS (0.86) | FDPSMAPTSMN1; SMN2NPSR1LMNA | |
| SCHEMBL6582635 | 0.77 | FDPS (0.61) | FDPSMAPTSMN1; SMN2NPSR1LMNA | |
| SCHEMBL8890887 | 0.77 | FDPS (0.55) | FDPSMAPTSMN1; SMN2NPSR1LMNA | |
| SCHEMBL7545268 | 0.76 | MAPT (0.60) | FDPSMAPTSMN1; SMN2NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | disclosed |
| WO-2009135590-A1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (FR) | 2009-11-12 | — | — | WO | disclosed |