Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | FDPS | P14324 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6229249 | 0.87 | FDPS (0.63) | MAPTSMN1; SMN2LMNANPSR1HTT | |
| SCHEMBL18873955 | 0.86 | MAOA (0.53) | MAPTSMN1; SMN2LMNANPSR1HTT | |
| SCHEMBL18874197 | 0.85 | MAOA (0.50) | MAPTSMN1; SMN2LMNANPSR1HTT | |
| SCHEMBL13620624 | 0.84 | FDPS (0.53) | MAPTSMN1; SMN2LMNANPSR1HTT | |
| SCHEMBL19242996 | 0.82 | FDPS (0.73) | MAPTSMN1; SMN2LMNANPSR1HTT | |
| SCHEMBL18874317 | 0.82 | FDPS (0.51) | MAPTSMN1; SMN2LMNANPSR1HTT | |
| SCHEMBL28653547 | 0.82 | ALDH1A1 (0.74) | MAPTSMN1; SMN2LMNANPSR1HTT | |
| SCHEMBL13620714 | 0.81 | MAOB (0.47) | MAPTSMN1; SMN2LMNANPSR1HTT | |
| SCHEMBL9078005 | 0.81 | FDPS (0.72) | MAPTSMN1; SMN2LMNANPSR1HTT | |
| SCHEMBL31331562 | 0.81 | FDPS (0.72) | MAPTSMN1; SMN2LMNANPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | disclosed |
| WO-2009135590-A1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (FR) | 2009-11-12 | — | — | WO | disclosed |