Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.65 |
| ▸ | FTO | Q9C0B1 | 9/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17970196 | 0.88 | MAPT (0.61) | MEN1MAPTHTTKMT2AUSP2 | |
| SCHEMBL23085041 | 0.87 | MEN1 (0.72) | MEN1MAPTHTTKMT2AUSP2 | |
| SCHEMBL13620744 | 0.87 | MEN1 (0.68) | MEN1MAPTHTTKMT2AUSP2 | |
| SCHEMBL13620673 | 0.84 | FTO (0.54) | MEN1MAPTHTTKMT2AUSP2 | |
| SCHEMBL9626406 | 0.84 | FTO (0.81) | MEN1MAPTHTTKMT2AFTO | |
| SCHEMBL18677730 | 0.84 | MAPT (0.77) | MEN1MAPTHTTKMT2AUSP2 | |
| SCHEMBL20353147 | 0.82 | MAPT (0.78) | MEN1MAPTHTTKMT2AUSP2 | |
| Fluorescein Diacetate SCHEMBL31658971 | 0.82 | MAPT (1.00) | MEN1MAPTHTTKMT2AUSP2 | |
| Fluorescein Diacetate SCHEMBL29353816 | 0.82 | MAPT (1.00) | MEN1MAPTHTTKMT2AUSP2 | |
| Fluorescein Diacetate SCHEMBL29453229 | 0.82 | MAPT (1.00) | MEN1MAPTHTTKMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420396-B2 | For delivering DNA/RNA into cells | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2013-04-16 | — | — | US | disclosed |
| US-8420396-B2 | For delivering DNA/RNA into cells | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2013-04-16 | — | — | US | disclosed |
| EP-1204430-B1 | CONJUGATES AND METHODS FOR THE PRODUCTION THEREOF, AND THEIR USE FOR TRANSPORTING MOLECULES VIA BIOLOGICAL MEMBRANES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-11-04 | — | — | EP | disclosed |
| US-20080071069-A1 | CONJUGATES AND PROCESSES FOR THEIR PREPARATION AND THEIR USE FOR TRANSPORTING MOLECULES ACROSS BIOLOGICAL MEMBRANES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-03-20 | — | — | US | disclosed |
| US-20080071069-A1 | CONJUGATES AND PROCESSES FOR THEIR PREPARATION AND THEIR USE FOR TRANSPORTING MOLECULES ACROSS BIOLOGICAL MEMBRANES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080071069-A1 | CONJUGATES AND PROCESSES FOR THEIR PREPARATION AND THEIR USE FOR TRANSPORTING MOLECULES ACROSS BIOLOGICAL MEMBRANES | EPCAM, ABCB1, ABCB11 | MEN1 877/4885MAPT 2324/4885HTT 2122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.