Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 9/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1024927 | 0.87 | MAPT (0.66) | FTOMAPTMEN1KMT2ALMNA | |
| SCHEMBL29349570 | 0.87 | MAPT (0.66) | FTOMAPTMEN1KMT2ALMNA | |
| SCHEMBL29382186 | 0.86 | ALDH1A1 (0.52) | FTOMAPTMEN1KMT2ALMNA | |
| SCHEMBL20420116 | 0.86 | ALDH1A1 (0.52) | FTOMAPTMEN1KMT2ALMNA | |
| SCHEMBL13620673 | 0.83 | FTO (0.54) | FTOMAPTMEN1KMT2ALMNA | |
| SCHEMBL12639984 | 0.82 | MEN1 (0.77) | FTOMAPTMEN1KMT2ALMNA | |
| SCHEMBL29403728 | 0.82 | MEN1 (0.77) | FTOMAPTMEN1KMT2ALMNA | |
| SCHEMBL9538912 | 0.81 | FTO (0.69) | FTOMAPTMEN1KMT2ALMNA | |
| SCHEMBL10145450 | 0.81 | MAPT (0.58) | FTOMAPTMEN1KMT2ALMNA | |
| SCHEMBL20419954 | 0.80 | ALDH1A1 (0.49) | FTOMAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204430-B1 | CONJUGATES AND METHODS FOR THE PRODUCTION THEREOF, AND THEIR USE FOR TRANSPORTING MOLECULES VIA BIOLOGICAL MEMBRANES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-11-04 | — | — | EP | disclosed |