Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 9/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20420116 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MEN1MAPTHTTKMT2A | |
| SCHEMBL20419954 | 0.92 | ALDH1A1 (0.49) | ALDH1A1MEN1MAPTHTTKMT2A | |
| SCHEMBL13212097 | 0.88 | ALDH1A1 (0.52) | ALDH1A1MEN1MAPTHTTKMT2A | |
| SCHEMBL30378493 | 0.88 | ALDH1A1 (0.52) | ALDH1A1MEN1MAPTHTTKMT2A | |
| SCHEMBL13620743 | 0.86 | FTO (0.57) | ALDH1A1MEN1MAPTHTTKMT2A | |
| SCHEMBL1024927 | 0.86 | MAPT (0.66) | ALDH1A1MEN1MAPTHTTKMT2A | |
| SCHEMBL29349570 | 0.86 | MAPT (0.66) | ALDH1A1MEN1MAPTHTTKMT2A | |
| SCHEMBL10123085 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MEN1MAPTHTTKMT2A | |
| SCHEMBL6663204 | 0.83 | MEN1 (0.75) | ALDH1A1MEN1MAPTHTTKMT2A | |
| SCHEMBL29663660 | 0.83 | MEN1 (0.75) | ALDH1A1MEN1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12631620-B2 | Methods of generating organoids for high throughput screening of drugs | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2026-05-19 | — | — | US | disclosed |
| EP-4667562-A1 | THREE-DIMENSIONAL HEPATOCYTE TISSUE AND METHOD FOR PRODUCING SAME | Toppan Holdings Inc. (JP) | 2025-12-24 | — | — | EP | disclosed |
| US-12492380-B2 | Methods for the production of hepatocytes | FUJIFILM Cellular Dynamics, Inc. (US) | 2025-12-09 | — | — | US | disclosed |
| US-20250368962-A1 | THREE-DIMENSIONAL HEPATIC TISSUE AND METHOD OF MANUFACTURING THE SAME | TOPPAN HOLDINGS INC. (JP) | 2025-12-04 | — | — | US | disclosed |
| US-20250356959-A1 | Toxicity Prediction Of Compounds In Cellular Structures | SANOFI SA (FR) | 2025-11-20 | — | — | US | disclosed |
| US-20250356483-A1 | Quality Control Of In-Vitro Analysis Sample Output | SANOFI SA (FR) | 2025-11-20 | — | — | US | disclosed |
| EP-4605905-A1 | QUALITY CONTROL OF IN-VITRO ANALYSIS SAMPLE OUTPUT | Sanofi (FR) | 2025-08-27 | — | — | EP | disclosed |
| EP-4605904-A1 | TOXICITY PREDICTION OF COMPOUNDS IN CELLULAR STRUCTURES | Sanofi (FR) | 2025-08-27 | — | — | EP | disclosed |
| US-20250228899-A1 | GENERATING AND UTILIZING ADULT HEPATOCYTE ORGANOIDS | UNIVERSITY OF WASHINGTON (US) | 2025-07-17 | — | — | US | disclosed |
| CN-120051813-A | Quality control of in vitro analysis sample output | 赛诺菲 | 2025-05-27 | — | — | CN | disclosed |
| EP-2920223-B1 | MOISTURE INDICATING HYDROPHILIC POLYURETHANE | MOELNLYCKE HEALTH CARE AB (SE) | 2023-07-12 | — | — | EP | disclosed |
| WO-2023070060-A1 | GENERATING AND UTILIZING ADULT HEPATOCYTE ORGANOIDS | UNIVERSITY OF WASHINGTON (US) | 2023-04-27 | — | — | WO | disclosed |
| EP-3426766-B1 | METHOD FOR CONTINUOUS BIOSENSING | YISSUM RESEARCH AND DEVELOPMENT COMPANY OF THE HEBREW UNIV OF JERUSALEM LTD (IL) | 2022-12-28 | — | — | EP | disclosed |
| WO-2022191222-A1 | BILE DUCT CHIP AND USE THEREOF | 国立大学法人京都大学 | 2022-09-15 | — | — | WO | disclosed |
| WO-2022181880-A1 | METHOD FOR CONSTRUCTING HUMAN PLURIPOTENT STEM CELL-DERIVED LIVER ORGANOID HAVING ENHANCED DRUG METABOLIC POTENTIAL AND LIVER ORGANOID CONSTRUCTED BY SAME METHOD | 한국화학연구원 | 2022-09-01 | — | — | WO | disclosed |
| US-20220220440-A1 | METHODS FOR THE PRODUCTION OF HEPATOCYTES | FUJIFILM Cellular Dynamics, Inc. (US) | 2022-07-14 | — | — | US | disclosed |
| EP-3966315-A1 | METHODS FOR THE PRODUCTION OF HEPATOCYTES | FUJIFILM Cellular Dynamics, Inc. (US) | 2022-03-16 | — | — | EP | disclosed |
| CN-114134198-A | Reagent, device and method for rapidly counting eukaryotic microorganisms | 国家粮食和物资储备局科学研究院 | 2022-03-04 | — | — | CN | disclosed |
| CN-114144514-A | Method for producing hepatocytes | 富士胶片细胞动力公司 | 2022-03-04 | — | — | CN | disclosed |
| US-20220042975-A1 | METHODS OF GENERATING ORGANOIDS FOR HIGH THROUGHPUT SCREENING OF DRUGS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2022-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12631620-B2 | Methods of generating organoids for high throughput screening of drugs | HGF, UGT1A10, TGFB2 | ALDH1A1 2701/4885MEN1 3518/4885MAPT 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.