Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | HPGD | P15428 | 7/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13620845 | 0.92 | ALDH1A1 (0.46) | MAPTALDH1A1KDM4EHPGDUSP2 | |
| SCHEMBL30682 | 0.85 | ALDH1A1 (0.65) | MAPTALDH1A1KDM4EHPGDUSP2 | |
| SCHEMBL29627559 | 0.85 | ALDH1A1 (0.65) | MAPTALDH1A1KDM4EHPGDUSP2 | |
| SCHEMBL30096340 | 0.85 | ALDH1A1 (0.65) | MAPTALDH1A1KDM4EHPGDUSP2 | |
| SCHEMBL20405140 | 0.81 | ALDH1A1 (0.57) | MAPTALDH1A1KDM4EHPGDUSP2 | |
| SCHEMBL4159029 | 0.80 | NPC1 (0.67) | MAPTALDH1A1KDM4EHPGDUSP2 | |
| SCHEMBL28774905 | 0.80 | KDM4E (0.55) | MAPTALDH1A1KDM4EHPGDUSP2 | |
| SCHEMBL987895 | 0.79 | ALDH1A1 (0.68) | MAPTALDH1A1KDM4EHPGDUSP2 | |
| SCHEMBL29531231 | 0.79 | ALDH1A1 (0.68) | MAPTALDH1A1KDM4EHPGDUSP2 | |
| SCHEMBL12304263 | 0.79 | KDM4E (0.62) | MAPTALDH1A1KDM4EHPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622520-B2 | Light reflecting polymeric articles containing benzoxazolyl-napthalene optical brighteners | MATTEL, INC (US) | 2009-11-24 | — | — | US | disclosed |