Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27098087 | 0.86 | TUBB4A (0.45) | TRPA1CYP3A4NOX1CA1CA2 | |
| SCHEMBL6050007 | 0.80 | CYP3A4 (0.50) | TRPA1CYP3A4TP53KDM4EMEN1 | |
| SCHEMBL15119377 | 0.78 | NOX1 (0.46) | NOX1CA1CA2CA9CA5A | |
| SCHEMBL13658553 | 0.78 | CA1 (0.42) | NOX1CA1CA2CA9CA5A | |
| SCHEMBL30808855 | 0.74 | NOX1 (0.40) | NOX1CA1CA2CA9CA5A | |
| SCHEMBL28607967 | 0.73 | HTR3E (0.46) | CYP3A4NOX1CA1CA2CA9 | |
| SCHEMBL28253685 | 0.73 | NOX1 (0.46) | CYP3A4NOX1CA1CA2CA9 | |
| SCHEMBL16002306 | 0.73 | NOX1 (0.42) | TRPA1CYP3A4NOX1CA1CA2 | |
| SCHEMBL13496979 | 0.73 | NEU3 (0.40) | NOX1CA1CA2CA9CA5A | |
| SCHEMBL31682371 | 0.72 | CA1 (0.45) | NOX1CA1CA2CA9CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964361-B2 | Rigidized trimethine cyanine dyes | CARNEGIE MELLON UNIVERSITY (US) | 2011-06-21 | — | — | US | disclosed |
| US-20090281279-A1 | Rigidized trimethine cyanine dyes | CARNEGIE MELLON UNIVERSITY (US) | 2009-11-12 | — | — | US | disclosed |
| US-7408062-B2 | Rigidized trimethine cyanine dyes | CARNEGIE MELLON UNIVERSITY (US) | 2008-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281279-A1 | Rigidized trimethine cyanine dyes | CD47, TLN1, TPM4 | TRPA1 501/4885CYP3A4 1841/4885NOX1 3162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.