Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1362922 | 0.87 | PIK3CD (0.36) | HDAC6PIK3CDPDE4BPDE7A | |
| SCHEMBL1362258 | 0.85 | PDE4A (0.39) | HDAC6PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL1363979 | 0.83 | PDE4A (0.35) | HDAC6PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL1362193 | 0.81 | HDAC6 (0.36) | HDAC6PIK3CDPDE4BPDE7APDE4A | |
| SCHEMBL1363030 | 0.81 | GAA (0.44) | HDAC6PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL1362629 | 0.80 | PDE4B (0.47) | PIK3CDPDE4BPDE7A | |
| SCHEMBL1362211 | 0.79 | HDAC6 (0.32) | HDAC6 | |
| SCHEMBL1362112 | 0.77 | HDAC6 (0.37) | HDAC6PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL1363966 | 0.76 | TP53 (0.33) | HDAC6PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL1363041 | 0.71 | TP53 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8066977-B2 | Agent for permanent hair waving containing heterocyclic mercapto compound | SHOWA DENKO K.K. (JP) | 2011-11-29 | — | — | US | disclosed |
| EP-1883454-B1 | AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND | SHOWA DENKO KK (JP) | 2009-11-04 | — | — | EP | disclosed |
| US-20090208439-A1 | Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound | SHOWA DENKO K.K. (JP) | 2009-08-20 | — | — | US | disclosed |
| EP-1883454-A2 | AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND | Showa Denko K.K. (JP) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006126729-A2 | AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND | SHOWA DENKO K.K. (JP) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090208439-A1 | Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound | NSD3, WNT3, MSRB3 | HDAC6 660/4885PIK3CD 4863/4885PDE4B 4539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.