SCHEMBL1362922

SCHEMBL1362922

CCN1C(=O)C(CS)N(CC(C)C)C1=O

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 2/20 0.36
F2 P00734 1/20 0.34
ELANE P08246 1/20 0.34
CTSG P08311 1/20 0.34
CTRC Q99895 1/20 0.34
HDAC6 Q9UBN7 2/20 0.33
USP2 O75604 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE7A Q13946 1/20 0.33
RGS4 P49798 1/20 0.30
RGS8 P57771 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1362152 0.87 HDAC6 (0.39) PIK3CDHDAC6PDE4BPDE7A
SCHEMBL1364091 0.84 F2 (0.41) F2ELANECTSGCTRCUSP2
SCHEMBL1362629 0.79 PDE4B (0.47) PIK3CDPDE4BPDE7A
SCHEMBL1362112 0.79 HDAC6 (0.37) F2ELANECTSGCTRCHDAC6
SCHEMBL1363519 0.79 F2 (0.37) PIK3CDF2ELANECTSGCTRC
SCHEMBL1361364 0.77 F2 (0.38) F2ELANECTSGCTRCUSP2
SCHEMBL1362214 0.77 GAA (0.44) F2ELANECTSGCTRCHDAC6
SCHEMBL1363028 0.73 F2 (0.41) F2ELANECTSGCTRCHDAC6
SCHEMBL1363979 0.72 PDE4A (0.35) F2ELANECTSGCTRCHDAC6
SCHEMBL1362258 0.70 PDE4A (0.39) HDAC6PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8066977-B2 Agent for permanent hair waving containing heterocyclic mercapto compound SHOWA DENKO K.K. (JP) 2011-11-29 US disclosed
EP-1883454-B1 AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND SHOWA DENKO KK (JP) 2009-11-04 EP disclosed
US-20090208439-A1 Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound SHOWA DENKO K.K. (JP) 2009-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090208439-A1 Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound NSD3, WNT3, MSRB3 PIK3CD 4863/4885F2 3730/4885ELANE 534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.