Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPRG | P23470 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28944666 | 0.85 | ALDH1A1 (0.37) | ALDH1A1ALOX15TSHRERCC5FEN1 | |
| SCHEMBL30452631 | 0.85 | TSHR (0.57) | ALDH1A1ALOX15TSHRERCC5FEN1 | |
| SCHEMBL1246006 | 0.85 | TSHR (0.57) | ALDH1A1ALOX15TSHRERCC5FEN1 | |
| SCHEMBL6905440 | 0.82 | GABRA1 (0.45) | ALDH1A1ALOX15TSHRERCC5FEN1 | |
| SCHEMBL28780507 | 0.82 | ALDH1A1 (0.32) | ALDH1A1ALOX15 | |
| SCHEMBL27568011 | 0.82 | ALDH1A1 (0.41) | ALDH1A1ALOX15TSHRERCC5FEN1 | |
| SCHEMBL1792164 | 0.82 | ALDH1A1 (0.48) | ALDH1A1ALOX15TSHRPTPN1CES2 | |
| SCHEMBL28036645 | 0.81 | IDO1 (0.42) | ALDH1A1ALOX15TSHRERCC5FEN1 | |
| SCHEMBL28780385 | 0.79 | ALDH1A1 (0.38) | ALDH1A1ALOX15TSHRERCC5FEN1 | |
| SCHEMBL13622162 | 0.79 | ALDH1A1 (0.38) | ALDH1A1ALOX15PTPN1HMGB1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103145693-B | Preparation method of imatinib | CHENGDU BAIYU SCIENCE & TECHNOLOGY PHARMACEUTICAL CO LTD | 2015-04-29 | — | — | CN | claimed |
| CN-110526859-A | A kind of preparation method of Rui Weina new intermediate and preparation method thereof and Rui Weinaxin | SHANDONG BESTCOMM PHARMACEUTICAL CO LTD | 2019-12-03 | — | — | CN | disclosed |
| CN-108570012-A | 1,3- benzoxazines -2,4 (3H)-derovatives and its preparation method and use | 中南大学 | 2018-09-25 | — | — | CN | disclosed |
| CN-103145693-B | Preparation method of imatinib | CHENGDU BAIYU SCIENCE & TECHNOLOGY PHARMACEUTICAL CO LTD | 2015-04-29 | — | — | CN | disclosed |
| US-7622612-B2 | Tricyclic derivatives and their use | CHEMTECH RESEARCH INCORPORATION (KR) | 2009-11-24 | — | — | US | disclosed |
| US-7622612-B2 | Tricyclic derivatives and their use | CHEMTECH RESEARCH INCORPORATION (KR) | 2009-11-24 | — | — | US | disclosed |
| US-20070021427-A1 | Novel tricyclic derivatives and their use | CHEMTECH RESEARCH INCORPORATION (KR) | 2007-01-25 | — | — | US | disclosed |
| US-20070021427-A1 | Novel tricyclic derivatives and their use | CHEMTECH RESEARCH INCORPORATION (KR) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021427-A1 | Novel tricyclic derivatives and their use | NFATC1, IL2, CCL2 | ALDH1A1 2078/4885ALOX15 1871/4885TSHR 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.