Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL920147 | 0.84 | SLC10A2 (0.59) | SLC10A2 | |
| SCHEMBL1361679 | 0.84 | SLC10A2 (0.78) | SLC10A2 | |
| SCHEMBL6222284 | 0.84 | SLC10A2 (1.00) | SLC10A2 | |
| SCHEMBL6222289 | 0.84 | SLC10A2 (1.00) | SLC10A2 | |
| SCHEMBL1362231 | 0.84 | SLC10A2 (0.58) | SLC10A2 | |
| SCHEMBL6921164 | 0.83 | SLC10A2 (1.00) | SLC10A2 | |
| SCHEMBL6827058 | 0.83 | SLC10A2 (1.00) | SLC10A2 | |
| SCHEMBL6829423 | 0.83 | SLC10A2 (1.00) | SLC10A2 | |
| SCHEMBL6827161 | 0.83 | SLC10A2 (1.00) | SLC10A2 | |
| SCHEMBL6220086 | 0.83 | SLC10A2 (1.00) | SLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067584-B2 | Benzothiazepine derivatives | ALBIREO AB (SE) | 2011-11-29 | — | — | US | disclosed |
| US-7226943-B2 | Benzothiepine ileal bile acid transport inhibitors | ASTRAZENECA AB (SE) | 2007-06-05 | — | — | US | disclosed |
| EP-1427718-B1 | BENZOTHIEPINE ILEAL BILE ACID TRANSPORT INHIBOTORS | ASTRAZENECA AB (SE) | 2006-11-15 | — | — | EP | disclosed |
| US-20060094884-A1 | Benzothiazepine and benzothiepine derivatives | ALBIREO AB (SE) | 2006-05-04 | — | — | US | disclosed |
| US-20050043393-A1 | Benzothiepine ileal bile acid transport inhibitors | ASTRAZENECA AB | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043393-A1 | Benzothiepine ileal bile acid transport inhibitors | SLC10A2, SLC10A1, ABCB11 | SLC10A2 1/4885 |
| US-20060094884-A1 | Benzothiazepine and benzothiepine derivatives | SLC10A2, SLC10A1, ABCB11 | SLC10A2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.