SCHEMBL13622305

SCHEMBL13622305

Cc1ccc(C=CC=Cc2ccc(N(C=C(c3ccccc3)c3ccc(C=O)cc3)c3ccc(C=CC=Cc4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.43
ALDH1A1 P00352 3/20 0.43
CYP3A4 P08684 1/20 0.43
HPGD P15428 1/20 0.43
PTGS2 P35354 1/20 0.41
CYP2A6 P11509 2/20 0.41
TRPM8 Q7Z2W7 2/20 0.41
CYP1B1 Q16678 2/20 0.40
KMT2A Q03164 4/20 0.40
GAA P10253 3/20 0.40
MEN1 O00255 3/20 0.40
MAPK1 P28482 1/20 0.38
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
CASP3 P42574 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17486890 0.92 ALDH1A1 (0.46) MAPTALDH1A1CYP3A4HPGDPTGS2
SCHEMBL13609992 0.92 ALDH1A1 (0.46) MAPTALDH1A1CYP3A4HPGDPTGS2
SCHEMBL17486892 0.91 CYP1B1 (0.45) MAPTALDH1A1CYP3A4HPGDPTGS2
SCHEMBL16807030 0.86 TRPM8 (0.42) MAPTALDH1A1CYP3A4HPGDPTGS2
SCHEMBL17486894 0.83 MAOB (0.48) MAPTALDH1A1CYP3A4TRPM8CYP1B1
SCHEMBL9972129 0.83 MAOB (0.48) MAPTALDH1A1CYP3A4TRPM8CYP1B1
SCHEMBL12377636 0.83 ALDH1A1 (0.41) MAPTALDH1A1CYP3A4HPGDPTGS2
SCHEMBL13242001 0.82 MAPT (0.45) MAPTALDH1A1CYP3A4HPGDPTGS2
SCHEMBL17486895 0.82 MAOB (0.47) MAPTALDH1A1CYP3A4CYP1B1KMT2A
SCHEMBL16807032 0.82 MAOB (0.47) MAPTALDH1A1CYP3A4TRPM8CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615326-B2 Electrophotographic photoconductor and image forming apparatus SHARP KABUSHIKI KAISHA (JP) 2009-11-10 US disclosed
US-20070281229-A1 Electrophotographic photoconductor and image forming apparatus SHARP KABUSHIKI KAISHA (JP) 2007-12-06 US disclosed
US-20070281229-A1 Electrophotographic photoconductor and image forming apparatus SHARP KABUSHIKI KAISHA (JP) 2007-12-06 US disclosed