Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17777233 | 1.00 | TDP1 (0.48) | TDP1TSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL15445146 | 1.00 | TDP1 (0.48) | TDP1TSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL13018490 | 1.00 | TDP1 (0.48) | TDP1TSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL13623017 | 0.86 | TDP1 (0.53) | TDP1TSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL8985841 | 0.83 | TDP1 (0.39) | TDP1TSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL8079639 | 0.81 | TDP1 (0.48) | TDP1TSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL14130601 | 0.81 | TDP1 (0.48) | TDP1TSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL14508563 | 0.79 | TDP1 (0.43) | TDP1TSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL2409417 | 0.79 | TDP1 (0.43) | TDP1TSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL8839807 | 0.79 | ALOX15 (0.44) | TDP1TSHRCHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448600-B1 | COMPOUNDS TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR | INSERM INST NAT DE LA SANTÉ ET DE LA RECH MÉDICALE (FR) | 2016-03-30 | — | — | EP | disclosed |
| WO-2009132478-A1 | SYNTHESIS OF TIMOSAPONIN BII | PHYTOPHARM PLC (GB) | 2009-11-05 | — | — | WO | disclosed |