Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079639 | 0.87 | TDP1 (0.48) | TDP1ALDH1A1LMNAHSD17B10USP2 | |
| SCHEMBL14130601 | 0.87 | TDP1 (0.48) | TDP1ALDH1A1LMNAHSD17B10USP2 | |
| SCHEMBL14508563 | 0.85 | TDP1 (0.43) | TDP1ALDH1A1LMNAHSD17B10USP2 | |
| SCHEMBL13623332 | 0.83 | TDP1 (0.42) | TDP1ALDH1A1LMNAHSD17B10USP2 | |
| SCHEMBL12019789 | 0.81 | TDP1 (0.41) | TDP1ALDH1A1LMNAHSD17B10USP2 | |
| SCHEMBL9152182 | 0.80 | TDP1 (0.43) | TDP1ALDH1A1LMNAHSD17B10USP2 | |
| SCHEMBL2026947 | 0.80 | TP53 (0.35) | ALDH1A1MAPTTSHRMEN1TP53 | |
| SCHEMBL28226699 | 0.80 | ALDH1A1 (0.38) | ALDH1A1MAPTTSHRTP53 | |
| SCHEMBL13622762 | 0.79 | TDP1 (0.48) | TDP1ALDH1A1LMNAHSD17B10USP2 | |
| SCHEMBL17777233 | 0.79 | TDP1 (0.48) | TDP1ALDH1A1LMNAHSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116035205-A | Probiotic composition for regulating metabolism and preparation method thereof | 广东华南医药技术有限责任公司 | 2023-05-02 | — | — | CN | claimed |
| CN-118026842-A | Preparation method of chlorogenic acid with content of 50 | 江西省科学院应用化学研究所 | 2024-05-14 | — | — | CN | disclosed |
| CN-116035205-A | Probiotic composition for regulating metabolism and preparation method thereof | 广东华南医药技术有限责任公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-111929388-B | Extraction method, detection method and extraction device for flavors and fragrances in food | 广州检验检测认证集团有限公司 | 2021-04-06 | — | — | CN | disclosed |
| CN-111929388-A | Extraction method, detection method and extraction device for flavors and fragrances in food | 广州检验检测认证集团有限公司 | 2020-11-13 | — | — | CN | disclosed |
| CN-106631709-B | Method for extracting and nitrating hydroxytyrosol | 中国林业科学研究院林产化学工业研究所 | 2020-01-10 | — | — | CN | disclosed |
| WO-2019170204-A1 | SYNTHESIS OF PRECURSORS OF 2,5-FURANDICARBOXYLIC ACID | Københavns Universitet (DK) | 2019-09-12 | — | — | WO | disclosed |
| EP-2114917-B1 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL (JP) | 2016-08-10 | — | — | EP | disclosed |
| US-8933105-B2 | Pyrrole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-01-13 | — | — | US | disclosed |
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |
| WO-2010150840-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2010-12-29 | — | — | WO | disclosed |
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| US-20080262042-A1 | 1-[5-(2-Fluoropyridin-3-yl)-1-(phenylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine or a salt thereof; acid secretion inhibitor; potassium-competitive acid blocker | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-10-23 | — | — | US | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |
| US-4053476-A | 7-AZA-6-ALKOXY-1-TETRALONES | G. D. SEARLE & CO. (US) | 1977-10-11 | — | — | US | disclosed |
| US-4012391-A | 11β-Alkyl-2-azaestratrienes and intermediates | G. D. SEARLE & CO. (US) | 1977-03-15 | — | — | US | disclosed |
| US-4007194-A | Process and intermediates for manufacture of 2-azasterioids | G. D. SEARLE & CO. (US) | 1977-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262042-A1 | 1-[5-(2-Fluoropyridin-3-yl)-1-(phenylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine or a salt thereof; acid secretion inhibitor; potassium-competitive acid blocker | REN, HRH2, ATP4A | TDP1 4743/4885ALDH1A1 1650/4885LMNA 3758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.