Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14130601 | 1.00 | TDP1 (0.48) | TDP1ALDH1A1LMNAHSD17B10USP2 | |
| SCHEMBL8816454 | 0.90 | ALDH1A1 (0.46) | TDP1ALDH1A1LMNAHSD17B10USP2 | |
| SCHEMBL13737428 | 0.90 | TDP1 (0.42) | TDP1ALDH1A1LMNAHSD17B10USP2 | |
| Ammonia Solution, Strong SCHEMBL9691236 | 0.88 | ALDH1A1 (0.44) | TDP1ALDH1A1LMNAHSD17B10USP2 | |
| SCHEMBL2409417 | 0.87 | TDP1 (0.43) | TDP1ALDH1A1LMNAHSD17B10USP2 | |
| SCHEMBL14508563 | 0.87 | TDP1 (0.43) | TDP1ALDH1A1LMNAHSD17B10USP2 | |
| SCHEMBL13623332 | 0.85 | TDP1 (0.42) | TDP1ALDH1A1LMNAHSD17B10USP2 | |
| SCHEMBL12019789 | 0.83 | TDP1 (0.41) | TDP1ALDH1A1LMNAHSD17B10USP2 | |
| SCHEMBL304203 | 0.82 | TDP1 (0.54) | TDP1ALDH1A1LMNAHSD17B10USP2 | |
| SCHEMBL18880920 | 0.81 | LMNA (0.42) | TDP1ALDH1A1LMNAHSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009030733-A1 | METHOD FOR THE SYNTHESIS OF 4-ALKOXY-, 4-HYDROXY- AND 4-ARYLOXY-SUBSTITUTED TETRAHYDRO-FURO[3,4-B]FURAN-2(3H)-ONE COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2009-03-12 | — | — | WO | disclosed |
| WO-2008034598-A1 | METHOD FOR THE SYNTHESIS OF HEXAHYDROFURO (2, 3-B) FURAN-3-OL COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2008-03-27 | — | — | WO | disclosed |