Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14931970 | 1.00 | CHRM1 (0.35) | CHRM1GNAI3GNAO1GNAI1OPRM1 | |
| SCHEMBL14931971 | 1.00 | CHRM1 (0.35) | CHRM1GNAI3GNAO1GNAI1OPRM1 | |
| SCHEMBL14042635 | 0.82 | OPRM1 (0.31) | CHRM1GNAI3GNAO1GNAI1OPRM1 | |
| SCHEMBL1240986 | 0.81 | SMYD3 (0.31) | — | |
| SCHEMBL1240984 | 0.81 | SMYD3 (0.31) | — | |
| SCHEMBL17592377 | 0.81 | SMYD3 (0.31) | — | |
| SCHEMBL10203552 | 0.81 | CTSL (0.32) | — | |
| SCHEMBL20879747 | 0.80 | MEN1 (0.41) | CHRM1GNAI3GNAO1GNAI1OPRM1 | |
| Hydrochloric Acid SCHEMBL15520847 | 0.79 | GNAI3 (0.31) | GNAI3GNAO1GNAI1 | |
| SCHEMBL13618243 | 0.77 | OPRM1 (0.35) | CHRM1OPRM1OPRL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136850-A1 | MUSCARINIC RECEPTOR AGONITS USEFUL IN THE TREATMENT OF PAIN, ALZHEIMER'S DISEASE AND SCHIZOPHRENIA | ASTRAZENECA AB (SE) | 2009-11-12 | — | — | WO | disclosed |