Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090738 | 1.00 | KMT2A (0.44) | KMT2AMEN1ALDH1A1TSHRMAPK1 | |
| SCHEMBL2096559 | 0.98 | KMT2A (0.42) | KMT2AMEN1ALDH1A1TSHRMAPK1 | |
| SCHEMBL13622839 | 0.88 | SLC6A4 (0.42) | KMT2AMEN1ALDH1A1TSHRMAPK1 | |
| SCHEMBL2090736 | 0.81 | KMT2A (0.44) | KMT2AMEN1ALDH1A1TSHRMAPK1 | |
| SCHEMBL2096556 | 0.79 | KMT2A (0.42) | KMT2AMEN1ALDH1A1TSHRMAPK1 | |
| SCHEMBL3149066 | 0.79 | HTR2A (0.47) | KMT2AMEN1ALDH1A1TSHRMAPK1 | |
| SCHEMBL5430139 | 0.79 | LMNA (0.43) | KMT2AMEN1ALDH1A1TSHRMAPK1 | |
| SCHEMBL8171738 | 0.79 | KMT2A (0.42) | KMT2AMEN1ALDH1A1TSHRMAPK1 | |
| SCHEMBL7665233 | 0.79 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1TSHRMAPK1 | |
| SCHEMBL8363501 | 0.79 | KMT2A (0.42) | KMT2AMEN1ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136850-A1 | MUSCARINIC RECEPTOR AGONITS USEFUL IN THE TREATMENT OF PAIN, ALZHEIMER'S DISEASE AND SCHIZOPHRENIA | ASTRAZENECA AB (SE) | 2009-11-12 | — | — | WO | disclosed |