SCHEMBL1362285

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2454761	0.82	MEN1 (0.42)	MEN1KMT2ALMNAALDH1A1HTT
	SCHEMBL26932241	0.82	MEN1 (0.47)	NPSR1MEN1KMT2ALMNAALDH1A1
	SCHEMBL1684422	0.79	MEN1 (0.55)	MEN1KMT2ALMNAALDH1A1HTT
	SCHEMBL1363869	0.79	MEN1 (0.44)	MEN1KMT2ALMNAALDH1A1HTT
	SCHEMBL2457267	0.78	LMNA (0.44)	MEN1KMT2ALMNAALDH1A1HTT
	SCHEMBL2518702	0.78	RIPK1 (0.40)	MEN1KMT2ALMNAALDH1A1HTT
	SCHEMBL23832906	0.76	MEN1 (0.40)	MEN1KMT2ALMNAALDH1A1HTT
	SCHEMBL2452887	0.76	ALDH1A1 (0.39)	MEN1KMT2ALMNAALDH1A1HTT
	SCHEMBL23116262	0.76	MEN1 (0.51)	NPSR1MEN1KMT2ALMNAALDH1A1
	SCHEMBL67173	0.76	RIPK1 (0.56)	MEN1KMT2ALMNAALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.