Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 4/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21064497 | 1.00 | CA1 (0.50) | CA1OPRM1FDPSACE2SPHK1 | |
| SCHEMBL18508660 | 0.93 | CA1 (0.41) | CA1OPRM1FDPSACE2SPHK1 | |
| SCHEMBL11388436 | 0.84 | SMN1; SMN2 (0.36) | CA1LMNA | |
| SCHEMBL11056750 | 0.82 | — | — | |
| SCHEMBL24467918 | 0.82 | CPB2 (0.35) | CA1SPHK1 | |
| SCHEMBL9856778 | 0.82 | FFAR4 (0.47) | CA1FDPSACE2SPHK1LMNA | |
| SCHEMBL7743756 | 0.82 | FFAR4 (0.47) | CA1FDPSACE2SPHK1LMNA | |
| SCHEMBL2117652 | 0.81 | ALDH1A1 (0.33) | CA1LMNA | |
| SCHEMBL11388470 | 0.79 | TSHR (0.33) | CA1 | |
| SCHEMBL21028381 | 0.79 | EPHX1 (0.38) | CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286745-A1 | INHIBITION OF ALPHA-SYNUCLEIN AGGREGATION | ZAPALOID LIMITED | 2009-11-19 | — | — | US | disclosed |