Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633500 | 0.85 | HTR2A (0.30) | — | |
| SCHEMBL23052584 | 0.82 | CA1 (0.31) | CA1 | |
| SCHEMBL21064497 | 0.79 | CA1 (0.50) | CA1 | |
| SCHEMBL13622892 | 0.79 | CA1 (0.50) | CA1 | |
| SCHEMBL21081931 | 0.78 | KISS1R (0.35) | EPHX1KISS1R | |
| SCHEMBL21276538 | 0.78 | EPHX1 (0.39) | EPHX1KISS1R | |
| SCHEMBL11388436 | 0.77 | SMN1; SMN2 (0.36) | CA1 | |
| SCHEMBL18508660 | 0.76 | CA1 (0.41) | CA1 | |
| SCHEMBL24235560 | 0.76 | KISS1R (0.42) | EPHX1KISS1RCA1 | |
| SCHEMBL24467918 | 0.75 | CPB2 (0.35) | EPHX1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301301-B2 | Inhibitors of lysine gingipain | Cortexyme, Inc. (US) | 2019-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301301-B2 | Inhibitors of lysine gingipain | ENPEP, PHYKPL, PREP | EPHX1 1202/4885KISS1R 245/4885CA1 651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.