Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 6/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13622806 | 0.87 | MEN1 (0.31) | OPRM1ALDH1A1OPRD1 | |
| SCHEMBL13623043 | 0.83 | UBE2M (0.32) | OPRM1CCR5ALDH1A1OPRD1 | |
| SCHEMBL13622803 | 0.72 | MEN1 (0.32) | ALDH1A1HRH3 | |
| SCHEMBL13478933 | 0.72 | ALDH1A1 (0.42) | ALDH1A1HRH3 | |
| SCHEMBL13631253 | 0.71 | KMT2A (0.41) | OPRM1ALDH1A1HRH3OPRD1 | |
| SCHEMBL13622851 | 0.68 | HTR2A (0.35) | OPRM1ALDH1A1HRH3 | |
| SCHEMBL13631250 | 0.68 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL1134575 | 0.67 | — | — | |
| SCHEMBL1134576 | 0.67 | — | — | |
| SCHEMBL13618227 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136850-A1 | MUSCARINIC RECEPTOR AGONITS USEFUL IN THE TREATMENT OF PAIN, ALZHEIMER'S DISEASE AND SCHIZOPHRENIA | ASTRAZENECA AB (SE) | 2009-11-12 | — | — | WO | disclosed |