Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13623043 | 0.93 | UBE2M (0.32) | MEN1ALDH1A1KMT2AOPRM1OPRD1 | |
| SCHEMBL13622899 | 0.87 | OPRM1 (0.33) | ALDH1A1OPRM1OPRD1 | |
| SCHEMBL13622803 | 0.74 | MEN1 (0.32) | MEN1ALDH1A1KMT2A | |
| SCHEMBL13622805 | 0.72 | EPHX2 (0.33) | MEN1ALDH1A1KMT2A | |
| SCHEMBL13622797 | 0.70 | HTR2A (0.34) | MEN1ALDH1A1KMT2AOPRM1 | |
| SCHEMBL1134576 | 0.69 | — | — | |
| SCHEMBL13618227 | 0.69 | — | — | |
| SCHEMBL1134575 | 0.69 | — | — | |
| SCHEMBL13622851 | 0.68 | HTR2A (0.35) | MEN1ALDH1A1KMT2AOPRM1 | |
| SCHEMBL4349887 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136850-A1 | MUSCARINIC RECEPTOR AGONITS USEFUL IN THE TREATMENT OF PAIN, ALZHEIMER'S DISEASE AND SCHIZOPHRENIA | ASTRAZENECA AB (SE) | 2009-11-12 | — | — | WO | disclosed |