Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 4/20 | 0.35 |
| ▸ | BRS3 | P32247 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 4/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13622972 | 0.81 | ASIC3 (0.44) | ERCC5FEN1ALDH1A1ASIC3IDH1 | |
| SCHEMBL13615811 | 0.78 | IDH1 (0.43) | ALDH1A1ASIC3IDH1BRS3LOXL2 | |
| SCHEMBL4312364 | 0.77 | ASIC3 (0.43) | ERCC5FEN1ALDH1A1ASIC3IDH1 | |
| SCHEMBL13629651 | 0.72 | ASIC3 (0.48) | ALDH1A1ASIC3IDH1BRS3NOS1 | |
| SCHEMBL13615880 | 0.70 | ASIC3 (0.46) | ALDH1A1ASIC3IDH1BRS3NOS1 | |
| SCHEMBL3913528 | 0.69 | LIMK1 (0.46) | KDM4EMEN1MAPTKMT2A | |
| SCHEMBL20390647 | 0.69 | ASIC3 (0.48) | ALDH1A1ASIC3IDH1BRS3NOS1 | |
| SCHEMBL13681316 | 0.68 | LOXL2 (0.50) | ASIC3LOXL2NOS3NOS2 | |
| SCHEMBL12680208 | 0.66 | ASIC3 (0.44) | ALDH1A1ASIC3IDH1NOS1KDM4E | |
| SCHEMBL13680693 | 0.65 | CCR1 (0.50) | ALDH1A1NOS1KDM4EMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137737-A2 | ANTI-BACTERIAL ACTIVITY OF 9-HYDROXY DERIVATIVES OF 6, 11-BICYCLOLIDES | ENANTA PHARMACEUTICALS, INC. (US) | 2009-11-12 | — | — | WO | disclosed |