Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 4/20 | 0.41 |
| ▸ | PGK2 | P07205 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3390400 | 0.88 | PGK1 (0.52) | PGK1PGK2PTPN5PTPN1 | |
| SCHEMBL9445936 | 0.81 | PGK1 (0.45) | PGK1PGK2RIPK1CYP1A2CYP2C19 | |
| SCHEMBL1338013 | 0.80 | PGK1 (0.44) | PGK1PGK2RIPK1PTPN5 | |
| SCHEMBL27887459 | 0.80 | PGK1 (0.41) | PGK1PGK2TP53BP1PTPN5PTPN1 | |
| SCHEMBL2031911 | 0.80 | TSHR (0.43) | PGK1PGK2PTPN5ALDH1A1TP53 | |
| SCHEMBL29024551 | 0.80 | PGK1 (0.53) | PGK1PGK2CA1MMP2PTPN5 | |
| SCHEMBL1352934 | 0.79 | HDAC3 (0.39) | PGK1PGK2MMP2CA14ALDH1A1 | |
| SCHEMBL1556937 | 0.78 | PTPN1 (0.52) | MEN1KMT2ASMN1; SMN2PGK1PGK2 | |
| Hydrogen Peroxide SCHEMBL8609891 | 0.78 | PTPN1 (0.52) | MEN1KMT2ASMN1; SMN2PGK1PGK2 | |
| SCHEMBL4538998 | 0.78 | CES2 (0.41) | PGK1PGK2L3MBTL1GAAPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5032682-A | — | — | None | — | — | JP | disclosed |
| CN-104341265-A | Novel 1,2-benzophenanthrene derivative as well as preparation method and application thereof | NANJING YOUSIBEITE PHOTOELECTRIC MATERIAL CO LTD | 2015-02-11 | — | — | CN | disclosed |
| US-8084449-B2 | Dual pharmacophores—PDE4-muscarinic antagonistics | GLAXO GROUP LIMITED (GB) | 2011-12-27 | — | — | US | disclosed |
| US-8071588-B2 | Dual pharmacophores—PDE4-muscarinic antagonistics | GLAXO GROUP LIMITED (GB) | 2011-12-06 | — | — | US | disclosed |
| US-8067408-B2 | Dual pharmacophores—PDE4-muscarinic antagonistics | GLAXO GROUP LIMITED (GB) | 2011-11-29 | — | — | US | disclosed |
| US-20090203677-A1 | Dual Pharmacophores - PDE4-Muscarinic Antagonistics | GLAXO GROUP LIMITED (GB) | 2009-08-13 | — | — | US | disclosed |
| US-20090203657-A1 | Dual Pharmacophores - PDE4-Muscarinic Antagonistics | GLAXO GROUP LIMITED (GB) | 2009-08-13 | — | — | US | disclosed |
| JP-H0532682-A | USE OF BENZYLPHOSPHONIC ACID DERIVATIVE FOR TREATMENT OF DISEASE CAUSED BY VIRUS | HOECHST AG | 1993-02-09 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203677-A1 | Dual Pharmacophores - PDE4-Muscarinic Antagonistics | PDE4A, PDE4B, PDE1A | MEN1 4113/4885KMT2A 2211/4885SMN1; SMN2 4433/4885 |
| US-20090203657-A1 | Dual Pharmacophores - PDE4-Muscarinic Antagonistics | PDE4A, PDE1A, PDE4B | MEN1 3034/4885KMT2A 1064/4885SMN1; SMN2 2601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.