Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.31 |
| ▸ | GRN | P28799 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13623262 | 0.81 | NOS3 (0.36) | GRIA1EGLN1GRNSORT1 | |
| SCHEMBL20390770 | 0.78 | EGLN1 (0.32) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14302852 | 0.78 | EGLN1 (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13615808 | 0.77 | CPB2 (0.36) | GRIA1EGLN1 | |
| SCHEMBL13514074 | 0.76 | LMNA (0.50) | GRNSORT1 | |
| SCHEMBL4353130 | 0.75 | IDO1 (0.38) | EGLN1 | |
| SCHEMBL13623091 | 0.72 | NOS3 (0.48) | — | |
| SCHEMBL13514024 | 0.72 | EGLN1 (0.38) | EGLN1 | |
| SCHEMBL20390799 | 0.72 | GRIN2D (0.38) | — | |
| SCHEMBL14397900 | 0.71 | EGLN1 (0.38) | AOC3EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137737-A2 | ANTI-BACTERIAL ACTIVITY OF 9-HYDROXY DERIVATIVES OF 6, 11-BICYCLOLIDES | ENANTA PHARMACEUTICALS, INC. (US) | 2009-11-12 | — | — | WO | disclosed |