Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.41 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.40 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4292449 | 0.89 | KDM4E (0.48) | ALDH1A1KDM4EPOLBRECQLSMN1; SMN2 | |
| SCHEMBL4299243 | 0.87 | KDM4E (0.49) | ALDH1A1KDM4EPOLBRECQLSMN1; SMN2 | |
| SCHEMBL4298481 | 0.86 | KDM4E (0.48) | ALDH1A1KDM4EPOLBRECQLSMN1; SMN2 | |
| Lithium Ion SCHEMBL4298479 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4EPOLBRECQLSMN1; SMN2 | |
| SCHEMBL4784069 | 0.75 | CYP2C19 (0.60) | KDM4EPOLBSMN1; SMN2LMNAMAPT | |
| SCHEMBL2596342 | 0.72 | SMN1; SMN2 (0.53) | ALDH1A1KDM4ERECQLSMN1; SMN2LMNA | |
| SCHEMBL13943 | 0.69 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBRECQLSMN1; SMN2 | |
| SCHEMBL30497266 | 0.69 | HPGD (0.62) | ALDH1A1KDM4EPOLBRECQLSMN1; SMN2 | |
| SCHEMBL18395333 | 0.69 | KDM4E (0.56) | ALDH1A1KDM4EPOLBRECQLSMN1; SMN2 | |
| SCHEMBL30899119 | 0.68 | KCNH2 (0.46) | ALDH1A1KDM4EPOLBRECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090280106-A1 | Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090280106-A1 | Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use | ADCYAP1R1, VIPR2, ADCY2 | ALDH1A1 2368/4885KDM4E 2974/4885POLB 4806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.