Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29505906 | 0.81 | GABRP (0.60) | MAPTKDM4ETDP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10031594 | 0.81 | GABRP (0.60) | MAPTKDM4ETDP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2259011 | 0.80 | HCAR3 (0.40) | TDP1SMN1; SMN2HCAR3RAB9AGABRP | |
| SCHEMBL2632670 | 0.78 | HDAC1 (0.56) | MAPTKDM4ETDP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL15088738 | 0.78 | MAPT (0.46) | MAPTKDM4ETDP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL30004108 | 0.78 | KCNJ1 (0.46) | MAPTSMN1; SMN2L3MBTL1HCAR3RAB9A | |
| SCHEMBL8184672 | 0.78 | KCNJ1 (0.46) | MAPTSMN1; SMN2L3MBTL1HCAR3RAB9A | |
| SCHEMBL1877325 | 0.77 | NAPRT (0.60) | MAPTSMN1; SMN2L3MBTL1RAB9ANPC1 | |
| SCHEMBL567789 | 0.77 | MAPT (0.44) | MAPTKDM4ETDP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10066762 | 0.77 | MAPT (0.44) | MAPTKDM4ETDP1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090280106-A1 | Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090280106-A1 | Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use | ADCYAP1R1, VIPR2, ADCY2 | MAPT 4286/4885KDM4E 2974/4885TDP1 4059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.