Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | BLM | P54132 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13624122 | 0.90 | GSK3A (0.35) | TLR2BLMCYP2C19HIF1AMEN1 | |
| SCHEMBL13623807 | 0.85 | SMN1; SMN2 (0.42) | TLR2CYP2C19LMNACYP3A4HSD17B10 | |
| SCHEMBL25622581 | 0.81 | TLR2 (0.42) | TLR2HSD17B10PTGS1PTGS2MGLL | |
| SCHEMBL10018579 | 0.78 | MGLL (0.33) | TLR2PTGS1PTGS2MGLLFAAH | |
| Ether SCHEMBL515801 | 0.77 | GSK3A (0.33) | BLMCYP2C19HIF1ACYP1A2ALDH1A1 | |
| SCHEMBL277453 | 0.76 | SMN1; SMN2 (0.43) | BLMCYP2C19HIF1ALMNACYP1A2 | |
| SCHEMBL15892801 | 0.75 | MGLL (0.39) | BLMCYP2C19HIF1AMEN1LMNA | |
| SCHEMBL10018581 | 0.75 | MGLL (0.38) | MAPK1BLMCYP2C19HIF1AMEN1 | |
| SCHEMBL277801 | 0.75 | SMN1; SMN2 (0.42) | BLMCYP2C19HIF1ALMNACYP1A2 | |
| SCHEMBL12201716 | 0.74 | KAT2A (0.39) | MAPK1BLMCYP2C19HIF1AGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090280106-A1 | Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090280106-A1 | Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use | ADCYAP1R1, VIPR2, ADCY2 | TLR2 2445/4885MAPK1 3433/4885BLM 4607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.