Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.35 |
| ▸ | MGLL | Q99685 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | WRN | Q14191 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13623673 | 0.90 | TLR2 (0.40) | GSK3AGSK3BTLR2PTGS1PTGS2 | |
| SCHEMBL15892801 | 0.78 | MGLL (0.39) | GSK3AGSK3BPTGS1PTGS2MGLL | |
| SCHEMBL13623807 | 0.78 | SMN1; SMN2 (0.42) | TLR2ALDH1A1HPGDCYP2C19 | |
| Ether SCHEMBL515801 | 0.77 | GSK3A (0.33) | GSK3AGSK3BPTGS1PTGS2MGLL | |
| SCHEMBL25622581 | 0.77 | TLR2 (0.42) | TLR2PTGS1PTGS2MGLL | |
| SCHEMBL15892774 | 0.76 | HPGD (0.37) | GSK3AGSK3BPTGS1PTGS2MGLL | |
| SCHEMBL277453 | 0.76 | SMN1; SMN2 (0.43) | GSK3AGSK3BPTGS1PTGS2MGLL | |
| SCHEMBL10018579 | 0.75 | MGLL (0.33) | TLR2PTGS1PTGS2MGLLFAAH | |
| SCHEMBL10018581 | 0.75 | MGLL (0.38) | PTGS1PTGS2MGLLFAAHMEN1 | |
| SCHEMBL277801 | 0.75 | SMN1; SMN2 (0.42) | GSK3AGSK3BPTGS1PTGS2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090280106-A1 | Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-11-12 | — | — | US | disclosed |
| US-20090005297-A1 | Aprotinin Variants | BAYER HEALTHCARE AG (DE) | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090280106-A1 | Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use | ADCYAP1R1, VIPR2, ADCY2 | GSK3A 3754/4885GSK3B 3936/4885TLR2 2445/4885 |
| US-20090005297-A1 | Aprotinin Variants | PRSS1, SPINT2, SERPINB1 | GSK3A 2920/4885GSK3B 3136/4885TLR2 4843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.