Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.47 |
| ▸ | KHK | P50053 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18653502 | 0.88 | NR3C1 (0.58) | NR3C1ALDH1A1MAPTL3MBTL1HPGDS | |
| SCHEMBL18013554 | 0.82 | NR3C1 (0.55) | NR3C1HPGDSMAPK8MAPK10KHK | |
| SCHEMBL13623919 | 0.78 | MAPK10 (0.67) | MAPK8MAPK10 | |
| SCHEMBL13624663 | 0.77 | MAPK10 (0.49) | NR3C1ALDH1A1MAPTL3MBTL1HPGDS | |
| SCHEMBL13624505 | 0.76 | MAPK10 (0.55) | HPGDSMAPK8MAPK10 | |
| SCHEMBL1413313 | 0.76 | NR3C1 (1.00) | NR3C1 | |
| SCHEMBL13624133 | 0.75 | MAPK10 (0.54) | HPGDSMAPK8MAPK10 | |
| SCHEMBL13624667 | 0.75 | MAPK10 (0.51) | NR3C1MAPK8MAPK10 | |
| SCHEMBL13623928 | 0.73 | MAPK10 (0.48) | NR3C1MAPK8MAPK10 | |
| SCHEMBL13380594 | 0.73 | NR3C1 (0.83) | NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009142569-A1 | PHENYL OR PYRIDINYL SUBSTITUTED INDAZOLES DERIVATIVES | ASTRAZENECA AB (SE) | 2009-11-26 | — | — | WO | disclosed |