Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | PIP4K2A | P48426 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7577389 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HPGDSMN1; SMN2MAPTUSP2 | |
| SCHEMBL4377743 | 0.76 | SMN1; SMN2 (0.50) | ALDH1A1HPGDSMN1; SMN2MAPTUSP2 | |
| SCHEMBL4377745 | 0.76 | SMN1; SMN2 (0.50) | ALDH1A1HPGDSMN1; SMN2MAPTUSP2 | |
| SCHEMBL12568146 | 0.75 | USP2 (0.57) | ALDH1A1HPGDSMN1; SMN2MAPTUSP2 | |
| SCHEMBL13002979 | 0.74 | ALDH1A1 (0.57) | ALDH1A1HPGDSMN1; SMN2MAPTUSP2 | |
| SCHEMBL78225 | 0.73 | ALDH1A1 (0.51) | ALDH1A1HPGDSMN1; SMN2MAPTUSP2 | |
| SCHEMBL11936018 | 0.73 | USP2 (0.52) | ALDH1A1HPGDSMN1; SMN2MAPTUSP2 | |
| SCHEMBL19547053 | 0.73 | USP2 (0.52) | ALDH1A1SMN1; SMN2MAPTUSP2PKM | |
| SCHEMBL11142367 | 0.72 | ALDH1A1 (0.74) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL4368253 | 0.72 | GAA (0.52) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291945-A1 | CYSTEINE PROTEASE INHIBITORS | TEIJIN PHARMA LIMITED (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20090291945-A1 | CYSTEINE PROTEASE INHIBITORS | TEIJIN PHARMA LIMITED (JP) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291945-A1 | CYSTEINE PROTEASE INHIBITORS | CTSE, SPINT2, CTSF | ALDH1A1 2506/4885HPGD 1352/4885SMN1; SMN2 4525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.