Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13159635 | 0.81 | SMN1; SMN2 (0.56) | KCNQ2ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL28228807 | 0.78 | ALDH1A1 (0.50) | KCNQ2ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL4368253 | 0.76 | GAA (0.52) | ALDH1A1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL4368258 | 0.76 | GAA (0.52) | ALDH1A1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL22673231 | 0.76 | ALDH1A1 (0.50) | KCNQ2ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL6228918 | 0.73 | ALDH1A1 (0.52) | KCNQ2ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL8342797 | 0.73 | ALDH1A1 (0.55) | KCNQ2ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL12310422 | 0.73 | KCNQ2 (0.67) | KCNQ2ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL12260392 | 0.73 | KCNQ2 (0.67) | KCNQ2ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL18574037 | 0.73 | ALDH1A1 (0.49) | KCNQ2ALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291945-A1 | CYSTEINE PROTEASE INHIBITORS | TEIJIN PHARMA LIMITED (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20090291945-A1 | CYSTEINE PROTEASE INHIBITORS | TEIJIN PHARMA LIMITED (JP) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291945-A1 | CYSTEINE PROTEASE INHIBITORS | CTSE, SPINT2, CTSF | KCNQ2 3491/4885ALDH1A1 2506/4885L3MBTL1 3079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.