Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27715897 | 0.88 | CYP3A4 (0.49) | TSHRCYP3A4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1755350 | 0.85 | TSHR (0.48) | TSHRALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL13497997 | 0.84 | ALDH1A1 (0.46) | CYP3A4ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28433503 | 0.82 | MAPT (0.50) | TSHRCYP3A4ALDH1A1L3MBTL1GAA | |
| SCHEMBL1735030 | 0.82 | POLB (0.49) | TSHRCYP3A4ALDH1A1L3MBTL1MAPT | |
| SCHEMBL27352232 | 0.81 | ALDH1A1 (0.45) | TSHRALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL1645808 | 0.81 | VCAM1 (0.50) | CYP3A4ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL16462859 | 0.81 | LMNA (0.48) | CYP3A4ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL26343367 | 0.79 | TSHR (0.51) | TSHRALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL13034135 | 0.79 | CYP3A4 (0.56) | TSHRCYP3A4ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141050-A2 | LINEAR SELF-ELIMINATING OLIGOMERS | KTB TUMORFORSCHUNGSGESELLSCHAFT MBH (DE) | 2009-11-26 | — | — | WO | disclosed |