Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17900079 | 0.84 | MAOB (0.41) | MAOBGRM2CHKAHTR2AAPP | |
| SCHEMBL19651371 | 0.84 | FDFT1 (0.47) | MAOBGRM2CHKAHTR2AAPP | |
| SCHEMBL16848654 | 0.82 | RARB (0.51) | MAOBGRM2CHKAHTR2AAPP | |
| SCHEMBL16848650 | 0.82 | RARB (0.51) | MAOBGRM2CHKAHTR2AAPP | |
| SCHEMBL17855855 | 0.82 | CHKA (0.35) | MAOBGRM2CHKAHTR2AAPP | |
| SCHEMBL16748099 | 0.81 | CYP17A1 (0.57) | GRM2CHKACYP3A4PDE3BPDE3A | |
| SCHEMBL16922714 | 0.81 | APP (0.53) | MAOBGRM2APPTAAR1 | |
| SCHEMBL19993271 | 0.80 | PTGS1 (0.38) | MAOBGRM2APPCYP3A4TAAR1 | |
| SCHEMBL16941050 | 0.80 | PTGS1 (0.46) | MAOBGRM2TAAR1PTGS1PDE3B | |
| SCHEMBL9057929 | 0.80 | ALDH1A1 (0.52) | GRM2HTR2AAPPCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512920-B1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
| US-20180188586-A1 | PROCESS OF PREPARING A LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2018-07-05 | — | — | US | disclosed |
| US-20180187081-A1 | PROCESS OF PREPARING A LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2018-07-05 | — | — | US | disclosed |
| WO-2018050573-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE | MERCK PATENT GMBH (DE) | 2018-03-22 | — | — | WO | disclosed |
| US-20180016499-A1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2018-01-18 | — | — | US | disclosed |
| US-20180004045-A1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2018-01-04 | — | — | US | disclosed |
| US-20170357131-A1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2017-12-14 | — | — | US | disclosed |
| US-20170342324-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2017-11-30 | — | — | US | disclosed |
| US-20170342324-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2017-11-30 | — | — | US | disclosed |
| WO-2016096081-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2016-06-23 | — | — | WO | disclosed |
| US-7623214-B2 | Liquid crystal materials | DOW CORNING CORPORATION (US) | 2009-11-24 | — | — | US | disclosed |
| US-20090115957-A1 | Liquid crystal materials | DOW SILICONES CORPORATION | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342324-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MTX1, S100A11, MCRS1 | MAOB 2561/4885GRM2 133/4885CHKA 3503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.