Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TTR | P02766 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | DHFR | P00374 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16673243 | 0.89 | MEN1 (0.49) | ALDH1A1TTRKDM4EMEN1USP2 | |
| SCHEMBL19478323 | 0.86 | TTR (0.46) | ALDH1A1TTRKDM4EMEN1USP2 | |
| SCHEMBL2094489 | 0.86 | TTR (0.46) | ALDH1A1TTRKDM4EMEN1USP2 | |
| SCHEMBL1773966 | 0.86 | TTR (0.46) | ALDH1A1TTRKDM4EMEN1USP2 | |
| SCHEMBL412535 | 0.86 | ESR1 (0.55) | ALDH1A1TTRKDM4EMEN1USP2 | |
| SCHEMBL1046583 | 0.86 | ACHE (0.50) | ALDH1A1TTRKDM4EMEN1USP2 | |
| SCHEMBL11545227 | 0.86 | TAAR1 (0.50) | ALDH1A1TTRKDM4EMEN1USP2 | |
| SCHEMBL18561607 | 0.86 | MEN1 (0.50) | ALDH1A1TTRKDM4EMEN1USP2 | |
| SCHEMBL22585210 | 0.86 | TTR (0.46) | ALDH1A1TTRKDM4EMEN1USP2 | |
| SCHEMBL412228 | 0.85 | MEN1 (0.49) | ALDH1A1TTRKDM4EMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996016980-A1 | MORPHOLINOETHYLAMIDE DERIVATIVES | NOVARTIS AG (CH) | 1996-06-06 | — | — | WO | disclosed |