Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.33 |
| ▸ | SMOX | Q9NWM0 | 1/20 | 0.32 |
| ▸ | SAT1 | P21673 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ADH7 | P40394 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13097521 | 0.93 | KDM1A (0.81) | KDM1ACYP2C19CYP1A2MEN1GLA | |
| SCHEMBL13097522 | 0.91 | KDM1A (0.86) | KDM1ACYP2C19CYP1A2MEN1GLA | |
| SCHEMBL13097505 | 0.91 | KDM1A (0.86) | KDM1ACYP2C19CYP1A2MEN1GLA | |
| SCHEMBL12951421 | 0.91 | KDM1A (0.85) | KDM1ACYP2C19CYP1A2MEN1GLA | |
| SCHEMBL13611317 | 0.88 | KDM1A (0.91) | KDM1ACYP2C19CYP1A2MEN1GLA | |
| SCHEMBL13097526 | 0.88 | KDM1A (0.90) | KDM1ACYP2C19CYP1A2MEN1GLA | |
| SCHEMBL13097518 | 0.88 | KDM1A (0.90) | KDM1ACYP2C19CYP1A2MEN1GLA | |
| SCHEMBL12951515 | 0.88 | KDM1A (0.90) | KDM1ACYP2C19CYP1A2MEN1GLA | |
| SCHEMBL23468531 | 0.86 | KDM1A (0.71) | KDM1ACYP2C19CYP1A2MEN1GLA | |
| SCHEMBL12951514 | 0.86 | KDM1A (0.95) | KDM1ACYP2C19CYP1A2MEN1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275664-A1 | NOVEL POLYAMINE ANALOG CONJUGATES AND QUINONE CONJUGATES AS THERAPIES FOR CANCERS AND PROSTATE DISEASES | PROGEN PHARMACEUTICALS, INC. | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275664-A1 | NOVEL POLYAMINE ANALOG CONJUGATES AND QUINONE CONJUGATES AS THERAPIES FOR CANCERS AND PROSTATE DISEASES | CTSB, CTSL, CTSV | KDM1A 3178/4885CYP2C19 2936/4885CYP1A2 3658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.