SCHEMBL13624831

SCHEMBL13624831

CC(C)(C)c1cc(/C=[N+](\[O-])Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc(C(C)(C)C)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
MEN1 O00255 4/20 0.45
TSHR P16473 4/20 0.45
KMT2A Q03164 4/20 0.45
CYP1A2 P05177 3/20 0.45
CYP3A4 P08684 3/20 0.45
BLM P54132 3/20 0.45
HIF1A Q16665 3/20 0.45
NPSR1 Q6W5P4 3/20 0.45
MAPK1 P28482 3/20 0.45
MAPT P10636 3/20 0.45
ATM Q13315 2/20 0.45
USP2 O75604 1/20 0.45
CYP2D6 P10635 1/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
GAA P10253 4/20 0.45
HTT P42858 3/20 0.45
LMNA P02545 3/20 0.45
GALR3 O60755 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6735300 0.88 SIRT1 (0.43) ALDH1A1MEN1TSHRKMT2ACYP1A2
SCHEMBL6269589 0.76 SMN1; SMN2 (0.50) ALDH1A1MEN1TSHRKMT2ACYP1A2
SCHEMBL11443703 0.75 ALDH1A1 (0.57) ALDH1A1MEN1TSHRKMT2ACYP1A2
SCHEMBL6738995 0.74 MEN1 (0.45) ALDH1A1MEN1TSHRKMT2ACYP1A2
SCHEMBL6738999 0.74 SMN1; SMN2 (0.45) ALDH1A1MEN1TSHRKMT2ACYP1A2
SCHEMBL6729105 0.73 SMN1; SMN2 (0.47) ALDH1A1MEN1TSHRKMT2ACYP1A2
SCHEMBL283499 0.69 ALDH1A1 (0.59) ALDH1A1MEN1TSHRKMT2ACYP1A2
SCHEMBL1821480 0.68 PTGS1 (0.74) ALDH1A1MEN1TSHRKMT2ACYP1A2
SCHEMBL39559 0.68 ALDH1A1 (0.63) ALDH1A1MEN1TSHRKMT2ACYP1A2
SCHEMBL1821479 0.68 PTGS1 (0.74) ALDH1A1MEN1TSHRKMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1718271-B1 STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS BASF SE (DE) 2014-10-08 EP disclosed
US-7618644-B2 Sterically hindered amine salts having an N-(alkoxy, cycloalkoxy or aralkoxy)2,2,6,6-tetraalkylsubstituted piperidine moiety; discoloration inhibition, colorfastness CIBA SPECIALTY CHEMICALS CORP. (US) 2009-11-17 US disclosed
US-7618618-B2 Stabilized body care products, household products, textiles and fabrics CIBA SPECIALTY CHEMICALS CORP. (US) 2009-11-17 US disclosed
US-20090074681-A1 Sterically hindered amine salts having an N-(alkoxy, cycloalkoxy or aralkoxy)2,2,6,6-tetraalkylsubstituted piperidine moiety; discoloration inhibition, colorfastness LUPIA JOSEPH A 2009-03-19 US disclosed
US-7429545-B2 Stabilized body care products, household products, textiles and fabrics CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-09-30 US disclosed
US-20080009550-A1 Stabilized body care products, household products, textiles and fabrics LUPIA JOSEPH A 2008-01-10 US disclosed
US-20070294837-A1 Stabilized body care products, household products, textiles and fabrics LUPIA JOSEPH A 2007-12-27 US disclosed
US-7309682-B2 Stabilized body care products, household products, textiles and fabrics CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090074681-A1 Sterically hindered amine salts having an N-(alkoxy, cycloalkoxy or aralkoxy)2,2,6,6-tetraalkylsubstituted piperidine moiety; discoloration inhibition, colorfastness DEK, CUTA, ANKK1 ALDH1A1 332/4885MEN1 4734/4885TSHR 1976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.